Rid·Ich+ is recommended as the best chemical treatment for Ich, (white spot disease), having been originally developed decades ago for professional aquaculture, public aquariums, and government use in treating fishes. Other than refinement in ingredients, it has continued to remain as the foremost scientifically developed chemical treatment for Ich white spot disease. Efficacy is improved and the treatment time is often reduced when compared to treatment with either the chemicals malachite or formalin alone. Additionally, the Rid·Ich+ formula utilizes the less common but also less toxic chloride salt of malachite green (this is the same salt used in Kordon's Malachite Green).

Kordon's Rid·Ich+ is a combination of two powerful medications which have proven effective in the control of many diseases of freshwater fishes caused by external protozoan (single cell) parasites such as white spot disease, Ichthyophthiriasis, Costia, Trichodina, Chilodonella and saltwater external parasites such as Cryptocaryon and Amyloodinium . The medication can also treat fungal infections in fishes.

The recommended treatment concentration of Rid·Ich+ should be approached with caution, carefully observing the reactions of the treated fishes and ceasing treatment if any undue stress is noted. Remember, when the first outward signs of Ich (scattered spots) are noticed, the fish is often quite heavily parasitic in the mouth and gills - lowering the fish's ability to withstand additional stress. The weaker the fishes' condition, the poorer its response will be to any medication. Rid·Ich+ has been shown to be reasonably safe for use on fishes which normally cannot tolerate malachite green alone.